Ingredient

Thuja plicata leaf extract

Thuja plicata leaf extract is flagged for pregnancy, breastfeeding, trying to conceive, postpartum and general use. The concern behind the strongest flag is absorbed into the body and fetal development.

By Team TruvaLast checked

Verdict by profile

Truva checks every ingredient against six profiles. Jump to any of them for the full assessment.

Strongest verdict
Not Recommended
Its verdict for pregnancy, the profile this one is worst in
Profiles flagged
5 of 6
Counting avoid, high risk and medium risk
Irritancy
2 of 5
Higher means more likely to sting or redden
PregnancyAVOID

Thuja plicata leaf extract and pregnancy

Not Recommended

Thuja plicata leaf extract contains thujone, a compound known to be neurotoxic and potentially teratogenic in sufficient concentrations. While the extract form used in cosmetics contains lower thujone levels than pure essential oils, the compound can still be absorbed through the skin. According to traditional herbal medicine warnings and toxicology research, thujone-containing plants like Thuja should be avoided during pregnancy due to potential effects on the developing nervous system and uterine stimulation properties. Several European regulatory bodies restrict or prohibit thujone-containing ingredients in products for pregnant women. While topical absorption is lower than oral consumption, the precautionary principle applies given the known toxicity of the active compounds. ACOG guidelines recommend avoiding essential oils and herbal extracts with known toxic compounds during pregnancy. Most obstetricians and dermatologists would advise choosing alternative antimicrobial and preservative ingredients that have established pregnancy safety profiles.

BreastfeedingAVOID

Thuja plicata leaf extract and breastfeeding

Not Recommended

Thuja plicata extract contains thujone and other terpenes that are lipophilic (fat-soluble) and could theoretically transfer into breast milk if absorbed systemically. While topical application involves lower absorption than oral consumption, the neurotoxic potential of thujone makes this a concern for breastfed infants. Traditional herbal medicine sources and lactation consultants generally recommend avoiding thujone-containing plants during breastfeeding. The infant's immature nervous system and detoxification pathways make them more vulnerable to even small amounts of neurotoxic compounds. The AAP and most pediatric guidelines suggest caution with herbal extracts containing bioactive compounds of this nature. While specific studies on topical Thuja extract during breastfeeding are lacking, the theoretical risk of thujone transfer and the availability of safer alternatives lead most healthcare providers to recommend avoidance, particularly if applied to large skin areas or near the breast.

PostpartumCAUTION

Thuja plicata leaf extract and postpartum

Caution Advised

For postpartum women who are not breastfeeding, the primary concerns with Thuja plicata extract are skin sensitivity and potential irritation, which may be heightened due to postpartum hormonal changes. The antimicrobial properties could be beneficial for preventing skin infections. Without the concern of infant exposure through milk, the risk level decreases to standard skin sensitivity concerns. However, given postpartum skin can be more reactive, patch testing is advisable before using products containing this extract, particularly on large areas or compromised skin barriers.

Trying to ConceiveAVOID

Thuja plicata leaf extract and trying to conceive

Not Recommended

Women trying to conceive should exercise the same caution as pregnant women with thujone-containing extracts. Since pregnancy may occur before a woman knows she is pregnant, avoiding potentially neurotoxic compounds during the conception period is advisable to protect early fetal development. Most fertility specialists and obstetricians recommend discontinuing use of herbal extracts with known toxic components when actively trying to conceive. The precautionary approach helps ensure no exposure during the critical early weeks of neural tube development, which occurs before most women realize they are pregnant.

PCOSSAFE

Thuja plicata leaf extract and PCOS

Safe to Use

Thuja plicata extract does not appear to have hormone-disrupting properties and poses no specific concerns for women with PCOS from an endocrine perspective. Its antimicrobial and anti-inflammatory properties could actually be beneficial for managing acne associated with PCOS. The antioxidant compounds in the extract may help reduce oxidative stress and inflammation, which are often elevated in PCOS. However, individuals with sensitive or acne-prone skin should be aware of potential irritation. There is no evidence that topical use of this plant extract affects androgen levels, insulin sensitivity, or other PCOS-related metabolic markers. The primary consideration is individual skin tolerance rather than hormonal concerns.

General UseCAUTION

Thuja plicata leaf extract and general use

Caution Advised

For the general population, Thuja plicata leaf extract in cosmetics poses primarily dermatological concerns rather than systemic toxicity when used at typical cosmetic concentrations. The extract provides antimicrobial and preservative benefits in formulations. The main concerns are contact dermatitis and allergic sensitization in susceptible individuals. People with sensitive skin or a history of reactions to essential oils or botanical extracts should exercise caution and perform patch testing before widespread use. While the thujone content in cosmetic formulations is generally much lower than in pure essential oils, regulatory bodies in some regions have set limits on thujone-containing ingredients. Products should be used as directed, avoiding application to large body areas or broken skin where absorption would be higher.

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Provenance

Where this came from

Truva summarises published guidance from bodies including ACOG, the FDA, the EU SCCS and the Cosmetic Ingredient Review. It has no access to your medical history and it is not a substitute for your doctor, dermatologist or midwife. These assessments have not been reviewed by a clinician, and nothing here is a diagnosis or a prescription. If you are pregnant, breastfeeding or being treated for PCOS, take the ingredient list to the person looking after you.

Assessment last pulled from the ingredient database on .

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