Ingredient

Petasites Japonicus Root Extract

Petasites Japonicus Root Extract is flagged for pregnancy and breastfeeding. The concern behind the strongest flag is absorbed into the body.

By Team TruvaLast checked

Verdict by profile

Truva checks every ingredient against six profiles. Jump to any of them for the full assessment.

Strongest verdict
Caution Advised
Its verdict for pregnancy, the profile this one is worst in
Profiles flagged
2 of 6
Counting avoid, high risk and medium risk
Irritancy
1 of 5
Higher means more likely to sting or redden
PregnancyCAUTION

Petasites Japonicus Root Extract and pregnancy

Caution Advised

Petasites Japonicus Root Extract comes from Japanese butterbur and is used in skincare for its anti-inflammatory and soothing properties. While the cosmetic extract should be processed to remove toxic pyrrolizidine alkaloids (PAs), concerns exist about the completeness of this purification process. The FDA and European Medicines Agency warn against internal use of butterbur during pregnancy due to potential liver toxicity from PAs and lack of safety data. While topical use is different from oral consumption, there is insufficient research on whether cosmetic-grade extracts are completely PA-free and whether any residual compounds could be absorbed through skin during pregnancy. Given that pregnancy increases caution around any potentially hepatotoxic substances, the theoretical risk remains a concern. Neither ACOG nor dermatological societies have issued specific guidance on topical butterbur use during pregnancy, likely due to limited data. Many healthcare providers recommend avoiding butterbur products during pregnancy as a precautionary measure, given the oral safety concerns and lack of specific topical safety studies. Pregnant women often choose alternative anti-inflammatory ingredients with more established safety profiles.

BreastfeedingCAUTION

Petasites Japonicus Root Extract and breastfeeding

Caution Advised

Petasites Japonicus Root Extract is an anti-inflammatory plant extract that should be processed to remove harmful pyrrolizidine alkaloids. However, the purity of cosmetic-grade extracts can vary by manufacturer. The FDA and medical literature strongly advise against oral butterbur use during breastfeeding due to potential PA toxicity, which could affect both mother's liver and potentially transfer to breast milk. While topical application results in lower systemic absorption than oral consumption, there is no specific research confirming that cosmetic butterbur extracts are safe for use during breastfeeding or that any absorbed components would not appear in breast milk. Due to the lack of safety data and the serious concerns about PAs in butterbur products, many lactation consultants and dermatologists recommend avoiding butterbur-containing cosmetics while breastfeeding. Alternative anti-inflammatory botanical extracts with better safety profiles are readily available.

PostpartumSAFE

Petasites Japonicus Root Extract and postpartum

Safe to Use

Petasites Japonicus Root Extract provides anti-inflammatory benefits that may be helpful for postpartum skin sensitivity and inflammation. When not breastfeeding, the primary concern is individual tolerance rather than infant safety. Postpartum women not breastfeeding can use products containing this extract with less concern, provided the product is from a reputable manufacturer that ensures PA removal. Those with sensitive skin or liver conditions should exercise caution with any butterbur-containing products.

Trying to ConceiveSAFE

Petasites Japonicus Root Extract and trying to conceive

Safe to Use

Petasites Japonicus Root Extract in topical cosmetics has no known effects on fertility or reproductive function. The concerns with butterbur primarily relate to liver toxicity from oral consumption of unpurified products, not fertility effects. Women trying to conceive can use skincare products containing this extract from reputable manufacturers. However, some women prefer to avoid ingredients with any safety questions during the preconception period and may opt for alternative anti-inflammatory ingredients.

PCOSSAFE

Petasites Japonicus Root Extract and PCOS

Safe to Use

Petasites Japonicus Root Extract has anti-inflammatory properties that may be beneficial for PCOS-related skin inflammation and acne. The extract does not have known hormonal activity and does not interact with androgen or estrogen receptors. Inflammation is a key component of PCOS pathophysiology, and topical anti-inflammatory ingredients may help manage skin symptoms. There is no evidence that butterbur extract affects insulin sensitivity or other metabolic aspects of PCOS. Individuals with PCOS can use products containing this extract for its anti-inflammatory benefits without concern for hormonal interference, provided the product is from a reputable source that ensures proper purification.

General UseSAFE

Petasites Japonicus Root Extract and general use

Safe to Use

Petasites Japonicus Root Extract is used in cosmetics for its anti-inflammatory and antioxidant properties. The extract can help calm irritated skin and reduce redness. Japanese butterbur has been used traditionally in Asian skincare for these soothing benefits. The main safety concern with butterbur is the presence of pyrrolizidine alkaloids (PAs) in raw plant material, which are toxic to the liver. Reputable cosmetic manufacturers process the extract to remove PAs, making it safe for topical use. The EU has strict regulations requiring cosmetic ingredients to be PA-free. When properly purified, butterbur extract has a good safety profile with minimal irritation potential. Consumers should choose products from established brands that follow good manufacturing practices and ensure PA removal. When properly processed, the extract is considered safe for topical use by most dermatologists. Individuals with known liver conditions may want to consult their healthcare provider before using products containing butterbur extract.

Same profiles

Everything else flagged for the same profiles

Keep reading

Related ingredients

Ingredients suggested in place of Petasites Japonicus Root Extract, each one with its own page here.

Ingredients that raise the same concerns.

Provenance

Where this came from

Truva summarises published guidance from bodies including ACOG, the FDA, the EU SCCS and the Cosmetic Ingredient Review. It has no access to your medical history and it is not a substitute for your doctor, dermatologist or midwife. These assessments have not been reviewed by a clinician, and nothing here is a diagnosis or a prescription. If you are pregnant, breastfeeding or being treated for PCOS, take the ingredient list to the person looking after you.

Assessment last pulled from the ingredient database on .

One ingredient is the easy case.

A label has thirty of them. Truva reads the whole list at once and answers for the profile you set: pregnancy, breastfeeding, postpartum, trying to conceive, PCOS, or general use.

Download on theApp Store