Ingredient

Kalanchoe Daigremontiana Leaf Extract

Kalanchoe Daigremontiana Leaf Extract is flagged for pregnancy, breastfeeding and trying to conceive. The concern behind the strongest flag is absorbed into the body and fetal development.

By Team TruvaLast checked

Verdict by profile

Truva checks every ingredient against six profiles. Jump to any of them for the full assessment.

Strongest verdict
Not Recommended
Its verdict for pregnancy, the profile this one is worst in
Profiles flagged
3 of 6
Counting avoid, high risk and medium risk
Irritancy
2 of 5
Higher means more likely to sting or redden
PregnancyAVOID

Kalanchoe Daigremontiana Leaf Extract and pregnancy

Not Recommended

Kalanchoe daigremontiana is a succulent plant extract used for moisturizing and soothing properties in skincare products. The plant is traditionally used in folk medicine, but its safety profile in cosmetics is not well-established. The primary concern during pregnancy stems from the presence of bufadienolides, which are cardiac glycoside compounds found in Kalanchoe species. These compounds can have physiological effects if absorbed systemically. While topical absorption rates are unknown, dermatologists generally recommend avoiding botanical extracts with known toxic compounds during pregnancy as a precautionary measure, especially when safer alternatives exist. No major regulatory body has issued specific guidance on this ingredient during pregnancy. However, given the presence of bioactive cardiac glycosides and the lack of safety data for topical use in pregnant women, most healthcare providers would recommend choosing well-studied moisturizing alternatives. If you're using a product containing this ingredient, consult with your obstetrician.

BreastfeedingCAUTION

Kalanchoe Daigremontiana Leaf Extract and breastfeeding

Caution Advised

As a botanical extract with cardiac glycoside compounds, Kalanchoe daigremontiana presents theoretical concerns for breastfeeding mothers. While topical application is generally considered to have minimal systemic absorption, the presence of bioactive compounds raises questions about potential transfer to breast milk. There are no published studies on the use of this ingredient during breastfeeding or its transfer to breast milk. Given the toxic potential of bufadienolides if ingested by infants, and the availability of well-studied moisturizing alternatives, many dermatologists would suggest using ingredients with better-established safety profiles during the breastfeeding period. If you're currently using products with this ingredient while breastfeeding, consider switching to alternatives like hyaluronic acid or glycerin, which have extensive safety data. Discuss any concerns with your healthcare provider or a dermatologist familiar with postpartum skincare.

PostpartumSAFE

Kalanchoe Daigremontiana Leaf Extract and postpartum

Safe to Use

For postpartum women who are not breastfeeding, Kalanchoe daigremontiana extract may provide moisturizing and soothing benefits without the concern of infant exposure through breast milk. The ingredient can help address skin hydration needs that often arise during the postpartum period. The main considerations are potential skin sensitivity and allergic reactions, which can be more common in individuals with compromised skin barriers. Start with patch testing if you have sensitive skin, and discontinue use if irritation occurs. While this ingredient is not as well-studied as conventional moisturizers, there are no specific postpartum contraindications for non-breastfeeding women.

Trying to ConceiveCAUTION

Kalanchoe Daigremontiana Leaf Extract and trying to conceive

Caution Advised

For women trying to conceive, the approach to this ingredient should mirror early pregnancy precautions. Since conception timing can be uncertain, and the first trimester is the most sensitive period for fetal development, it's prudent to avoid ingredients with unknown safety profiles and potentially bioactive compounds. Given the presence of cardiac glycosides in Kalanchoe species and the lack of safety data for reproductive outcomes, many healthcare providers recommend switching to well-studied moisturizing alternatives when actively trying to conceive. This precautionary approach ensures you're not exposed to potentially concerning compounds during the critical early weeks of pregnancy, which may occur before you know you're pregnant.

PCOSSAFE

Kalanchoe Daigremontiana Leaf Extract and PCOS

Safe to Use

Kalanchoe daigremontiana extract functions as a moisturizer and humectant in skincare products. For women with PCOS, adequate skin hydration is beneficial, particularly since PCOS-related hormonal fluctuations can affect skin texture and barrier function. There is no evidence or mechanism suggesting this botanical extract interferes with hormones or affects PCOS symptoms. The moisturizing properties may actually help manage skin concerns associated with PCOS, such as texture issues or irritation from acne treatments. Some Kalanchoe species have demonstrated anti-inflammatory properties in preliminary research, though specific studies on this species and PCOS are lacking. Women with PCOS can use products containing this ingredient without concern for hormonal interference. As with any skincare ingredient, individual skin sensitivity varies, so monitor for any irritation or allergic reactions, particularly if you have reactive skin.

General UseSAFE

Kalanchoe Daigremontiana Leaf Extract and general use

Safe to Use

For the general population, Kalanchoe daigremontiana leaf extract serves as a botanical moisturizing ingredient with potential soothing and antioxidant properties. It's used in various skincare formulations to provide hydration and may offer additional benefits from plant compounds, though extensive clinical research is limited. The main considerations for general use are individual skin sensitivity and potential allergic reactions. Some people may experience mild irritation or contact dermatitis from botanical extracts. The cardiac glycosides present in Kalanchoe species are primarily a concern with oral ingestion rather than topical application, where absorption is minimal in products with intact skin barriers. If you have sensitive skin or known plant allergies, perform a patch test before widespread use. Discontinue if you experience redness, itching, or irritation. While this ingredient is not as extensively studied as some conventional moisturizers, it can be safely used by most individuals as part of a regular skincare routine.

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Provenance

Where this came from

Truva summarises published guidance from bodies including ACOG, the FDA, the EU SCCS and the Cosmetic Ingredient Review. It has no access to your medical history and it is not a substitute for your doctor, dermatologist or midwife. These assessments have not been reviewed by a clinician, and nothing here is a diagnosis or a prescription. If you are pregnant, breastfeeding or being treated for PCOS, take the ingredient list to the person looking after you.

Assessment last pulled from the ingredient database on .

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