Ingredient

Griffonia Simplicifolia Seed Extract

Griffonia Simplicifolia Seed Extract is flagged for pregnancy and breastfeeding. The concern behind the strongest flag is absorbed into the body.

By Team TruvaLast checked

Verdict by profile

Truva checks every ingredient against six profiles. Jump to any of them for the full assessment.

Strongest verdict
Caution Advised
Its verdict for pregnancy, the profile this one is worst in
Profiles flagged
2 of 6
Counting avoid, high risk and medium risk
Irritancy
1 of 5
Higher means more likely to sting or redden
PregnancyCAUTION

Griffonia Simplicifolia Seed Extract and pregnancy

Caution Advised

Griffonia Simplicifolia Seed Extract is a botanical ingredient used in cosmetics for its antioxidant properties. The plant is known for containing 5-HTP (5-hydroxytryptophan), a serotonin precursor that is commonly used in oral supplements for mood support. While topical cosmetic use involves much lower concentrations than oral supplements and results in minimal systemic absorption, there is limited data specifically on topical use during pregnancy. Oral 5-HTP supplements are generally not recommended during pregnancy due to theoretical concerns about affecting serotonin levels in both mother and fetus. The American Pregnancy Association advises caution with serotonin-affecting substances during pregnancy. However, the risk from topical cosmetic application is likely much lower than from oral supplementation. Due to the presence of bioactive compounds and limited safety data for topical use during pregnancy, some practitioners recommend avoiding or limiting use of this ingredient as a precautionary measure. While the risk from topical application is likely minimal, alternative botanical antioxidants with more established safety profiles are available.

BreastfeedingCAUTION

Griffonia Simplicifolia Seed Extract and breastfeeding

Caution Advised

Griffonia Simplicifolia Seed Extract contains 5-HTP, a serotonin precursor. While topical cosmetic application results in much lower systemic exposure than oral supplementation, the compound's bioactive nature raises theoretical concerns. Oral 5-HTP supplements are generally not recommended during breastfeeding due to the potential for affecting both maternal and infant serotonin levels. While topical application is unlikely to result in significant absorption or milk transfer, specific studies on topical use during breastfeeding are lacking. Due to limited safety data and the theoretical concern about serotonin-affecting compounds during breastfeeding, some healthcare providers recommend avoiding this ingredient or choosing alternative botanical antioxidants with more established safety profiles. The actual risk from cosmetic use is likely low, but precaution is advised.

PostpartumSAFE

Griffonia Simplicifolia Seed Extract and postpartum

Safe to Use

Griffonia Simplicifolia Seed Extract is a botanical antioxidant used in cosmetics for its skin-conditioning properties. For postpartum women who are not breastfeeding, there are no specific contraindications. This ingredient can be safely used by postpartum women not breastfeeding. Its antioxidant properties may help protect and support skin health during the postpartum recovery period.

Trying to ConceiveSAFE

Griffonia Simplicifolia Seed Extract and trying to conceive

Safe to Use

Griffonia Simplicifolia Seed Extract used topically in cosmetics has minimal systemic absorption. While oral 5-HTP supplementation may have hormonal effects, topical cosmetic use is unlikely to affect fertility or hormone balance. Women trying to conceive can likely use products containing this ingredient safely, though some may choose to switch to alternative antioxidants with more established preconception safety data as a precautionary measure. Topical cosmetic use poses minimal risk to conception or early pregnancy.

PCOSSAFE

Griffonia Simplicifolia Seed Extract and PCOS

Safe to Use

Griffonia Simplicifolia Seed Extract is a botanical antioxidant with no known hormonal activity. It does not affect androgen levels, insulin sensitivity, or other metabolic factors related to PCOS. While the plant contains 5-HTP which affects serotonin when taken orally, topical cosmetic application does not result in significant systemic absorption. There are no contraindications for topical use in women with PCOS. This ingredient is safe for women with PCOS and may provide antioxidant benefits for skin health. It has no effects on hormone levels or PCOS-related metabolic function when used topically.

General UseSAFE

Griffonia Simplicifolia Seed Extract and general use

Safe to Use

Griffonia Simplicifolia Seed Extract is a botanical ingredient used in cosmetics for its antioxidant and skin-conditioning properties. While the plant is known for containing 5-HTP (used in oral supplements), topical cosmetic formulations use the extract primarily for antioxidant benefits. When used topically in cosmetics, this ingredient is generally well-tolerated with minimal risk of irritation. It is suitable for most skin types and provides antioxidant protection against environmental stressors. Both the EU and US regulatory frameworks allow the use of this botanical extract in cosmetic products. For the general public, topical use poses no significant safety concerns.

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Provenance

Where this came from

Truva summarises published guidance from bodies including ACOG, the FDA, the EU SCCS and the Cosmetic Ingredient Review. It has no access to your medical history and it is not a substitute for your doctor, dermatologist or midwife. These assessments have not been reviewed by a clinician, and nothing here is a diagnosis or a prescription. If you are pregnant, breastfeeding or being treated for PCOS, take the ingredient list to the person looking after you.

Assessment last pulled from the ingredient database on .

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