Ingredient

Cinchona Calisaya Extract

Cinchona Calisaya Extract is flagged for pregnancy, breastfeeding and trying to conceive. The concern behind the strongest flag is absorbed into the body and fetal development.

By Team TruvaLast checked

Verdict by profile

Truva checks every ingredient against six profiles. Jump to any of them for the full assessment.

Strongest verdict
Not Recommended
Its verdict for pregnancy, the profile this one is worst in
Profiles flagged
3 of 6
Counting avoid, high risk and medium risk
Irritancy
2 of 5
Higher means more likely to sting or redden
PregnancyAVOID

Cinchona Calisaya Extract and pregnancy

Not Recommended

Cinchona Calisaya Extract is derived from cinchona bark, which naturally contains quinine and related alkaloids. Quinine is a medication with known effects on the body and has historically been associated with uterine stimulation at medicinal doses. According to medical guidance, quinine-containing products warrant caution during pregnancy. While topical cosmetic concentrations are much lower than oral medicinal doses, the FDA classifies quinine as pregnancy category C due to potential effects on fetal development and uterine activity. The alkaloid content in this botanical extract raises similar theoretical concerns, even though systemic absorption from cosmetics is limited. Most obstetricians and dermatologists recommend avoiding quinine-containing botanical extracts during pregnancy as a precautionary measure. While serious adverse effects are unlikely from topical cosmetic use, safer alternatives are readily available.

BreastfeedingCAUTION

Cinchona Calisaya Extract and breastfeeding

Caution Advised

Cinchona bark extract contains quinine and related alkaloids that can be absorbed systemically and potentially transfer to breast milk. Quinine is known to pass into breast milk when taken orally as medication. While topical application in cosmetics involves much lower exposure than oral quinine, there is theoretical concern about infant exposure through breast milk. The AAD and lactation consultants generally recommend avoiding quinine-containing products while breastfeeding due to potential infant effects, even though topical absorption is limited. Many healthcare providers suggest postponing use of cinchona-containing products until after weaning. Safer botanical extracts without alkaloid content are preferable during the breastfeeding period.

PostpartumSAFE

Cinchona Calisaya Extract and postpartum

Safe to Use

For postpartum women not breastfeeding, the primary concerns with cinchona extract are photosensitivity and potential mild irritation rather than systemic effects. The extract provides antioxidant benefits. Women should use sun protection when using products containing this ingredient and monitor for any signs of sensitivity. Postpartum women without breastfeeding concerns can use this ingredient with appropriate precautions.

Trying to ConceiveCAUTION

Cinchona Calisaya Extract and trying to conceive

Caution Advised

Women trying to conceive should consider avoiding cinchona extract due to quinine content, applying similar precautions as pregnancy. It's generally recommended to discontinue use when actively trying to conceive. While topical absorption is limited, the theoretical concerns that apply during pregnancy suggest a cautious approach during the preconception period. Safer alternatives without alkaloid content are preferable for women planning pregnancy.

PCOSSAFE

Cinchona Calisaya Extract and PCOS

Safe to Use

Cinchona Calisaya Extract has antioxidant properties and no known hormonal effects relevant to PCOS. The extract is primarily valued for its astringent and conditioning properties in cosmetics. There are no documented concerns regarding cinchona extract use by women with PCOS. The ingredient does not interfere with androgen levels, insulin sensitivity, or other PCOS-related metabolic factors. Women with PCOS can use products containing this extract safely, though standard precautions for photosensitivity should be observed.

General UseSAFE

Cinchona Calisaya Extract and general use

Safe to Use

Cinchona Calisaya Extract is a botanical ingredient used in cosmetics for its astringent, antioxidant, and conditioning properties. It's derived from the bark that historically provided quinine for medicinal use. The main concerns for general consumers are photosensitivity and potential allergic reactions in sensitive individuals. Users should apply sun protection and discontinue use if irritation occurs. The concentrations used in cosmetics are generally well-tolerated. For non-pregnant, non-breastfeeding adults, this ingredient is considered relatively safe when used in appropriate cosmetic concentrations with proper sun protection.

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Provenance

Where this came from

Truva summarises published guidance from bodies including ACOG, the FDA, the EU SCCS and the Cosmetic Ingredient Review. It has no access to your medical history and it is not a substitute for your doctor, dermatologist or midwife. These assessments have not been reviewed by a clinician, and nothing here is a diagnosis or a prescription. If you are pregnant, breastfeeding or being treated for PCOS, take the ingredient list to the person looking after you.

Assessment last pulled from the ingredient database on .

One ingredient is the easy case.

A label has thirty of them. Truva reads the whole list at once and answers for the profile you set: pregnancy, breastfeeding, postpartum, trying to conceive, PCOS, or general use.

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